
You might not think about your gut when you look in the mirror—but your digestive system plays a big role in how your skin looks and feels.
The gut and skin are both barrier organs, meaning they protect your body from the outside world. When the gut barrier becomes imbalanced—due to factors like stress, processed foods, antibiotics, or lack of sleep—it can trigger low-grade inflammation throughout the body. That inflammation often shows up on the skin as redness, flares, or dryness.
This relationship is known as the gut–skin axis, and growing research shows that improving gut balance can lead to calmer, clearer skin.
When the gut is out of balance, it can disrupt the immune system and make chronic skin conditions harder to control. In fact, nearly 70% of your immune system resides in your gut, meaning that what happens there has a direct impact on inflammation throughout your body—including your skin.
For people with eczema, research shows that changes in the gut microbiome—particularly a decrease in beneficial bacteria like Lactobacillus and Bifidobacterium—can alter how the body regulates inflammation. This imbalance may increase the release of histamines and inflammatory cytokines, leading to more itching, dryness, and sensitivity.
In psoriasis, chronic inflammation in the gut can activate the same immune pathways involved in skin flares, including the IL-17 and IL-23 signaling pathways. When the gut barrier becomes “leaky,” inflammatory molecules can enter the bloodstream, amplifying immune overactivity in the skin. Supporting gut health helps calm this cycle of inflammation and restore immune balance—often resulting in fewer flares, smoother skin, and improved overall well-being.
There’s no single “gut-friendly” diet for everyone—but there are steps that can help your skin and digestion work together:
At Zest, we treat skin conditions as more than surface-level issues. We recognize that lasting control often starts from the inside out. Your care plan may include nutrition guidance, stress support, and behavioral strategies alongside medical treatment to help your skin thrive naturally.
Our goal is to help you understand the why behind your flares—and to build a care plan that restores balance to both your skin and your overall health.
Your gut and skin are deeply connected—when one is inflamed, the other often shows it. By nurturing your gut health through balanced nutrition, rest, and stress management, you’re also supporting clearer, calmer skin.
Have questions about how your diet or gut health could be affecting your skin? Send a message through your Zest portal—your care team can help you explore personalized ways to bring your skin (and your system) back into balance.
Get fast, expert-backed treatment and virtual dermatology care with Zest. Book a next-day appointment, message your dedicated care team 24/7, and get specialized support.
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