6 Best Hypochlorous Acid Sprays to Calm and Refresh Skin—Anytime, Anywhere

We’re not saying hypochlorous acid sprays can do everything…but these multitasking skin-care products do tackle an impressive array of issues. The active ingredient, hypochlorous acid, forms when chlorine reacts with water and has potent antimicrobial properties—making it an effective salve for skin conditions ranging from rosacea to sunburns and more. Rachel Day, MD, a board-certified dermatologist based in Coral Gables, Florida, explains it like this: “Hypochlorous acid is a naturally occurring molecule your immune system produces to help fight off infection and support healing. In dermatology, we use hypochlorous acid spray as a gentle topical formulation to reduce inflammation, calm irritated skin, and keep bacteria in check—without disrupting the skin barrier.”